BRCA1 Regulates GADD45 through Its Interactions with the OCT-1 and CAAT Motifs
نویسندگان
چکیده
منابع مشابه
BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs.
BRCA1, a breast and ovarian cancer susceptibility gene, has been implicated in gene regulation. Previous studies demonstrate that BRCA1 induces GADD45, a p53-regulated and stress-inducible gene that plays an important role in cellular response to DNA damage. However, the mechanism(s) by which BRCA1 regulates GADD45 remains unclear. In this report, we have shown that BRCA1 activation of the GADD...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1074/jbc.m110225200